Soft aim undetectable5/31/2023 ![]() Children of mothers who filled an opioid prescription were no more likely to be hospitalized for any reason compared to children born to mothers who did not (hazard ratio 0.98 95% CI 0.93 to 1.03). In the primary analysis, 2,962 (3.46%) children born to mothers who filled an opioid prescription were hospitalized, compared to 3,038 (3.55%) children born to mothers who did not receive an opioid. The median age was 32 years, 60.3% were primigravid, and 80.8% underwent cesarean delivery. ![]() Results: We studied 85,675 women who filled an opioid prescription within seven days of hospital discharge after delivery and 85,675 women who did not. ![]() Secondary outcomes included any emergency department visit, hospitalization for any injury, admission to an intensive care unit, hospitalization with resuscitation or assisted ventilation, and neonatal death. The primary outcome was neonatal readmission to hospital for any reason within 30 days of the maternal opioid prescription. We matched each to one woman who did not, matching on age, calendar year, mode of delivery, and logit of the propensity score. From this group we identified women who filled an opioid prescription within seven days of discharge. We identified all mother-infant pairs discharged from hospital alive within seven days of delivery. Methods: Population-based retrospective cohort study using propensity score matching in Ontario, Canada, from Septemto March 31, 2020. Research Question: Is postpartum maternal opioid therapy associated with adverse neonatal outcomes? 3 Unity Health, Toronto, Ontario, Canadaīackground: It is widely taught that maternal use of opioids while breastfeeding, and use of codeine in particular, can predispose neonates to opioid toxicity. Jonathan Zipursky 1,2, Tara Gomes 3,2, Karl Everett 2, Andrew Calzavara 2, Michael Paterson 2, Peter C Austin 2, Muhammad M Mamdani 3, David N Juurlink 1,2ġ Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. ![]() Postpartum Maternal Opioid Therapy and the Risk of Adverse Neonatal Outcomes
0 Comments
Leave a Reply. |